brain diseases

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

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Study Counts

Type	Study_count
Total_Studies	331
interventional	218
Observational	103
Registry	10

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type	Study_Count
Drug	62
Device	35
Drug|placebo	30
Procedure	14
Other	12
Biological	9
Dietary Supplement	9
Behavioral	5
Biological|placebo	4
Device|Drug	4
Diagnostic Test	4
Behavioral|Other	3
Biological|Drug	2
Device|Procedure	2
Dietary Supplement|Other	2
Dietary Supplement|placebo	2
Drug|Other	2
Behavioral|Drug|Other	1
Behavioral|Drug|placebo	1
Biological|Drug|Procedure	1
Biological|Other	1
Biological|Procedure	1
Combination Product	1
Device|Drug|Procedure	1
Device|Genetic|Radiation	1
Device|Other	1
Diagnostic Test|Drug	1
Dietary Supplement|Drug|Other	1
Dietary Supplement|Drug|placebo	1
Drug|Other|placebo	1
Drug|Other|placebo|Procedure	1
Drug|Procedure	1
Drug|Radiation	1
Other|Procedure|Radiation	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	83
India	12
China	11
Italy	10
NA	10
United Kingdom	9
Canada	8
Denmark	5
Egypt	5
France	5
Mexico	5
Spain	4
Finland|Sweden	3
Belgium	2
Belgium|Netherlands	2
Brazil	2
Hong Kong	2
Japan	2
Malaysia	2
Norway	2
Pakistan	2
Russian Federation	2
Sweden	2
Switzerland	2
Australia|New Zealand	1
Austria	1
Austria|Belgium|Estonia|Finland|Germany|Italy|Netherlands|Norway|Poland|Portugal|Spain|Switzerland	1
Bangladesh|India|Sri Lanka	1
Canada|United States	1
Finland|Netherlands|United Kingdom	1
Holy See (Vatican City State)|Italy	1
India|United Kingdom	1
Ireland|Netherlands|Sweden|United Kingdom	1
Korea, Republic of	1
Poland	1
Singapore	1
Spain|United States|Australia|Austria|Belgium|Bulgaria|Czechia|Denmark|Estonia|France|Germany|Hungary|Israel|Italy|Netherlands|New Zealand|Russian Federation	1
Thailand	1
Uganda	1
Ukraine	1
United States|Argentina|Brazil|Colombia	1
United States|Australia|Canada|China|Israel|Poland|Portugal|Spain	1
United States|Belgium|Denmark	1
United States|Canada|New Zealand|United Kingdom	1
United States|Canada|Puerto Rico	1
United States|Canada|United Kingdom	1
United States|Puerto Rico	1
United States|United Arab Emirates	1
United States|United Kingdom	1
Zambia	1

Sites per Study

Site_count	Study_Count
1	142
2	15
3	12
4	8
6	4
7	3
8	6
9	4
10	1
11	2
12	1
13	1
17	2
18	1
20	1
22	1
23	1
25	1
27	2
28	2
34	1
35	1
38	1
39	1
43	1
44	1
132	1
160	1

Phase

Phase	Study_Count
N/A	92
Phase 2	32
Phase 4	25
Phase 1	23
Phase 1/Phase 2	21
Phase 3	17
Phase 2/Phase 3	5
Early Phase 1	3

Number of Arms

Number_of_Arms	Count_of_Studies
1	53
2	118
3	20
4	9
5	2
6	1
7	1
25	1
NA	13

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	7.00000	2.0000	2.00000	4.00000	5.000	120.0	25.000	20.00
1st Qu.	15.50000	30.0000	13.50000	17.00000	40.000	127.0	184.000	42.00
Median	24.00000	60.0000	20.00000	30.00000	55.000	130.0	256.000	88.00
Mean	23.66667	251.9444	28.08696	51.80952	3221.062	142.6	2645.471	124.08
3rd Qu.	32.00000	134.5000	38.50000	60.00000	155.000	168.0	501.000	200.00
Max.	40.00000	8360.0000	80.00000	200.00000	100000.000	168.0	40000.000	424.00

Trial Group Type

group_type	Group_Count
Experimental	232
Active Comparator	94
Placebo Comparator	57
No Intervention	25
Other	21
NA	13
Sham Comparator	4

Intervention Model

intervention_model	Study_Count
Parallel Assignment	135
Single Group Assignment	62
Crossover Assignment	10
Sequential Assignment	5
NA	5
Factorial Assignment	1

Primary Purpose

primary_purpose	Study_Count
Treatment	146
Prevention	30
Diagnostic	19
Other	7
Basic Science	5
NA	5
Supportive Care	4
Device Feasibility	1
Health Services Research	1

Observational Studies

Studies by Country

Country	Study_Count
United States	39
Germany	9
France	7
China	5
Switzerland	4
United Kingdom	4
Denmark	3
Italy	3
NA	3
Sweden	3
Turkey	3
Canada	2
Egypt	2
Finland	2
Japan	2
Mexico	2
Hong Kong	1
India	1
Ireland|Sweden	1
Nigeria	1
Pakistan	1
Slovenia	1
United States|Canada|Germany|Switzerland	1
United States|Canada|Thailand|United Kingdom	1
United States|Canada|United Kingdom	1
United States|Germany	1

Sites per Study

Site_count	Study_Count
1	77
2	10
3	5
5	2
6	3
7	2
14	1
16	1
20	1
22	1

Enrollment Metrics

Measure	Observational
Min	5.000
1st Qu	39.500
Median	100.000
Mean	5367.262
3rd Qu	327.500
Max	500000.000

Observation Model

observational_model	Study_Count
Cohort	54
Case-Control	16
Case-Only	13
Other	9
Case Control	6
NA	4
Family-Based	1

Time Perspective

time_perspective	Study_Count
Prospective	80
Cross-Sectional	8
Retrospective	7
Other	4
NA	4

Registries

Studies by Country

Country	Study_Count
United Kingdom	2
United States	2
Austria	1
France	1
Germany	1
Italy	1
Turkey	1
United States|Brazil|Colombia|France|Spain	1

Sites per Study

Site_count	Study_Count
1	6
2	1
9	1
16	1
38	1

Enrollment Metrics

Measure	Registries
Min	10.00
1st Qu	162.50
Median	265.00
Mean	1239.90
3rd Qu	366.75
Max	10000.00

Registry Model

observational_model	Study_Count
Cohort	6
Case-Only	2
Case-Control	1
Other	1

Time Perspective

time_perspective	Study_Count
Prospective	7
Other	3

Follow-up

target_duration	Study_Count
10 Years	3
12 Months	1
2 Years	1
3 Months	1
4 Years	1
6 Months	1
6 Years	1
7 Days	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03409770	Optimising the Duration of Cooling in Mild Encephalopathy	https://ClinicalTrials.gov/show/NCT03409770	Recruiting	Thayyil, Sudhin	2022-06-30
NCT03396939	The Technology-assisted, High Intensive, Task-oriented Exercise Trial	https://ClinicalTrials.gov/show/NCT03396939	Active, not recruiting	Sunnaas Rehabilitation Hospital	2019-12-20
NCT03395717	Stroke Rehabilitation With Exoskeleton-assisted Gait.	https://ClinicalTrials.gov/show/NCT03395717	Completed	IRCCS San Raffaele	2018-11-01
NCT03380013	OMT to Improve Feeding After Hypothermia	https://ClinicalTrials.gov/show/NCT03380013	Completed	Maine Medical Center	2018-04-30
NCT03825848	The Influence of Post-transjugular Intrahepatic Portosystemic Shunt Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT03825848	Recruiting	Shanghai Zhongshan Hospital	2023-12-31
NCT03819764	Cost-effectiveness of Forced Aerobic Exercise for Stroke Rehabilitation	https://ClinicalTrials.gov/show/NCT03819764	Recruiting	The Cleveland Clinic	2023-08-31
NCT03360656	Transnasal Induction of Normothermia in Febrile Stroke Patients	https://ClinicalTrials.gov/show/NCT03360656	Recruiting	CoolTech LLC	2020-07-31
NCT03352310	Feasibility and Safety of Umbilical Cord Blood Transfusion in the Treatment of Neonatal Cerebral Ischemia and Anemia	https://ClinicalTrials.gov/show/NCT03352310	Recruiting	Mononuclear Therapeutics Ltd.	2020-06-30
NCT02544542	Clinical Trial of a New Rectum Cooling System on Patients of Hypoxic-ischemic Brain Damage	https://ClinicalTrials.gov/show/NCT02544542	Completed	Children’s Hospital of Chongqing Medical University	2016-10-31
NCT03295786	Clinical Study to Test the Safety of CDNF by Brain Infusion in Patients With Parkinson’s Disease	https://ClinicalTrials.gov/show/NCT03295786	Completed	Herantis Pharma Plc.	2019-12-19
NCT03253354	Neurostimulation for Dysphagia in Parkinson’s Disease	https://ClinicalTrials.gov/show/NCT03253354	Recruiting	University of Manchester	2020-04-30
NCT03230032	Pacifier Activated Device and Mother’s Voice in Infants at High-risk for Cerebral Palsy	https://ClinicalTrials.gov/show/NCT03230032	Recruiting	Nationwide Children’s Hospital	2021-06-30
NCT03209258	The Third, Intensive Care Bundle With Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial	https://ClinicalTrials.gov/show/NCT03209258	Recruiting	The George Institute for Global Health, China	2022-05-30
NCT03166215	Study of TAK-935 as an Adjunctive Therapy in Participants With Developmental and/or Epileptic Encephalopathies	https://ClinicalTrials.gov/show/NCT03166215	Completed	Takeda	2018-09-19
NCT03162653	Effect of Allopurinol for Hypoxic-ischemic Brain Injury on Neurocognitive Outcome	https://ClinicalTrials.gov/show/NCT03162653	Recruiting	University Hospital Tuebingen	2020-11-30
NCT03152188	Oral Fecal Transplant in Cirrhosis	https://ClinicalTrials.gov/show/NCT03152188	Completed	Virginia Commonwealth University	2018-11-12
NCT03138876	EEG Cap for Identification of Non-Convulsive Status Epilepticus	https://ClinicalTrials.gov/show/NCT03138876	Completed	Mayo Clinic	2018-08-16
NCT03123081	Role of Umbilical Cord Milking in the Management of Hypoxic-ischemic Encephalopathy in Neonates	https://ClinicalTrials.gov/show/NCT03123081	Recruiting	Jubilee Mission Medical College and Research Institute	2020-12-31
NCT03079284	Holding, Stress, and Bonding During Therapeutic Hypothermia	https://ClinicalTrials.gov/show/NCT03079284	Completed	Maine Medical Center	2017-09-23
NCT03079167	PAEAN - Erythropoietin for Hypoxic Ischaemic Encephalopathy in Newborns	https://ClinicalTrials.gov/show/NCT03079167	Recruiting	University of Sydney	2021-12-31
NCT03071861	Mild Encephalopathy in the Newborn Treated With Darbepoetin	https://ClinicalTrials.gov/show/NCT03071861	Recruiting	University of New Mexico	2019-10-31
NCT03071783	Intra-operative Feed Back on Traction Force During Vacuum Extraction: Safe Vacuum Extraction Alliance	https://ClinicalTrials.gov/show/NCT03071783	Completed	Karolinska Institutet	2018-06-15
NCT03065192	Safety and Efficacy Study of VY-AADC01 for Advanced Parkinson’s Disease	https://ClinicalTrials.gov/show/NCT03065192	Active, not recruiting	Neurocrine Biosciences	2021-12-31
NCT03027869	Normal Brain Imaging Database for Brain Disorder Studies	https://ClinicalTrials.gov/show/NCT03027869	Active, not recruiting	University of Manitoba	2020-03-11
NCT03024827	Cannabidiol in Children With Refractory Epileptic Encephalopathy	https://ClinicalTrials.gov/show/NCT03024827	Active, not recruiting	University of Saskatchewan	2020-02-01
NCT03020433	Novel Brain Stimulation Therapies in Stroke Guided Expressions of Plasticity	https://ClinicalTrials.gov/show/NCT03020433	Recruiting	The Cleveland Clinic	2019-12-31
NCT02957123	Intranasal Inhalations of Bioactive Factors Produced by M2 Macrophages in Patients With Organic Brain Syndrome	https://ClinicalTrials.gov/show/NCT02957123	Recruiting	Russian Academy of Medical Sciences	2020-11-30
NCT02951559	SOLFAMU Study of Nasal Brushing Collected OLFActory MUcosa Samples in the Diagnosis of Human Encephalopathies	https://ClinicalTrials.gov/show/NCT02951559	Recruiting	University of Turin, Italy	2021-02-28
NCT02941536	Correlation Between Circulating Tumor Cells and Brain Disease Control After Focal Radiotherapy for Metastases of Breast Cancer	https://ClinicalTrials.gov/show/NCT02941536	Completed	AC Camargo Cancer Center	2018-10-15
NCT02889939	High-intensity Training in an Enriched Environment in Late Phase After Stroke	https://ClinicalTrials.gov/show/NCT02889939	Completed	Göteborg University	2015-07-31
NCT02826941	Moderate Hypothermia in Neonatal Hypoxic Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT02826941	Completed	Medical University of South Carolina	2004-06-30
NCT02822027	Intravenous Immunoglobin Transfusion in Preterm Infants With Encephalopathy of Prematurity	https://ClinicalTrials.gov/show/NCT02822027	Recruiting	Daping Hospital and the Research Institute of Surgery of the Third Military Medical University	2021-12-01
NCT02812433	Sildenafil Administration to Treat Neonatal Encephalopathy	https://ClinicalTrials.gov/show/NCT02812433	Active, not recruiting	McGill University Health Centre/Research Institute of the McGill University Health Centre	2019-02-28
NCT02782208	Lipolytic Effects of GH in Hypopituitary Patients in Vivo	https://ClinicalTrials.gov/show/NCT02782208	Completed	University of Aarhus	2016-12-22
NCT02776189	Dexmedetomidine Verses Propofol for Paediatric MRI Brain	https://ClinicalTrials.gov/show/NCT02776189	Completed	Maharashtra University of Health Sciences	2014-03-31
NCT02684825	Detection of Silent Atrial Fibrillation aFter Ischemic StrOke	https://ClinicalTrials.gov/show/NCT02684825	Recruiting	Azienda Policlinico Umberto I	2018-06-30
NCT02636647	Fecal Transplant in Recurrent Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT02636647	Completed	Hunter Holmes Mcguire Veteran Affairs Medical Center	2016-08-31
NCT02621944	Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia	https://ClinicalTrials.gov/show/NCT02621944	Recruiting	University of Florida	2021-03-31
NCT02612155	A Multi-site Study of Autologous Cord Blood Cells for Hypoxic Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT02612155	Completed	Duke University	2019-08-05
NCT02795052	Neurologic Stem Cell Treatment Study	https://ClinicalTrials.gov/show/NCT02795052	Recruiting	MD Stem Cells	2022-06-30
NCT02551003	Neuroprotective Effect of Autologous Cord Blood Combined With Therapeutic Hypothermia Following Neonatal Encephalopathy	https://ClinicalTrials.gov/show/NCT02551003	Recruiting	Children’s Hospital of Fudan University	2020-12-30
NCT02550054	Erythropoietin in Premature Infants to Prevent Encephalopathy	https://ClinicalTrials.gov/show/NCT02550054	Recruiting	Children’s Hospital of Fudan University	2020-12-30
NCT02529202	Dexmedetomidine Pharmacokinetics in Neonates During Therapeutic Hypothermia	https://ClinicalTrials.gov/show/NCT02529202	Completed	Seattle Children’s Hospital	2016-11-30
NCT02431780	A Multicentre Clinical Investigation of a Decision Support Algorithm for Neonatal Seizure Detection	https://ClinicalTrials.gov/show/NCT02431780	Active, not recruiting	University College Cork	2017-02-28
NCT02387385	Hypothermia for Encephalopathy in Low and Middle-Income Countries Trial	https://ClinicalTrials.gov/show/NCT02387385	Active, not recruiting	Thayyil, Sudhin	2020-08-31
NCT02287077	Umbilical Cord Milking for Neonates With Hypoxic Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT02287077	Completed	Thomas Jefferson University	2016-10-31
NCT02256618	Autologous Cord Blood Cell Therapy for Neonatal Encephalopathy	https://ClinicalTrials.gov/show/NCT02256618	Completed	Neonatal Encephalopathy Consortium, Japan	2017-10-31
NCT02255617	Fecal Microbiota Transplantation (FMT) in the Management of Hepatic Encephalopathy (HE): a Pilot Study	https://ClinicalTrials.gov/show/NCT02255617	Completed	University of Alberta	2019-07-25
NCT02254863	UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells	https://ClinicalTrials.gov/show/NCT02254863	Recruiting	Duke University	2022-09-30
NCT02191267	Tau Imaging of Chronic Traumatic Encephalopathy	https://ClinicalTrials.gov/show/NCT02191267	Completed	Brigham and Women’s Hospital	2016-09-30
NCT02171104	MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis	https://ClinicalTrials.gov/show/NCT02171104	Recruiting	Masonic Cancer Center, University of Minnesota	2020-09-30
NCT02163837	Effect of Rifaximine on Sleep Disorders in Patients Suffering From Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT02163837	Completed	Centre Hospitalier Universitaire Saint Pierre	2015-07-31
NCT02158182	Lactulose, L-ornithine L-aspartate, or Rifaximin Versus Placebo for Preventing Hepatic Encephalopathy in Variceal Bleeding	https://ClinicalTrials.gov/show/NCT02158182	Completed	Hospital General de Mexico	2016-06-30
NCT02156232	Embolization of Large Spontaneous Portosystemic Shunts for the Prevention of Post-TIPS Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT02156232	Recruiting	Fourth Military Medical University	2020-12-31
NCT02154282	iPod Games in Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT02154282	Completed	Hunter Holmes Mcguire Veteran Affairs Medical Center	2016-07-31
NCT02106065	VA Cultivating Access to Resources, Education, and Skills for Dementia Caregivers	https://ClinicalTrials.gov/show/NCT02106065	Completed	VA Office of Research and Development	2019-09-30
NCT02103894	Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects	https://ClinicalTrials.gov/show/NCT02103894	Completed	Molecular NeuroImaging	2016-08-31
NCT02071394	Xenon and Cooling Therapy in Babies at High Risk of Brain Injury Following Poor Condition at Birth	https://ClinicalTrials.gov/show/NCT02071394	Active, not recruiting	University Hospitals Bristol NHS Foundation Trust	2019-10-07
NCT02070380	Crossover Comparison of MultiHance and Dotarem	https://ClinicalTrials.gov/show/NCT02070380	Completed	Bracco Diagnostics, Inc	2015-03-31
NCT01283152	Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic Encephalopathy.	https://ClinicalTrials.gov/show/NCT01283152	Completed	University of Texas Southwestern Medical Center	2012-06-30
NCT02056236	TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation	https://ClinicalTrials.gov/show/NCT02056236	Recruiting	University of Twente	2020-03-31
NCT02019784	Randomised Controlled Trial of Mechanistic Effects of Rifaximin in Cirrhosis and Chronic Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT02019784	Completed	King’s College Hospital NHS Trust	2016-06-30
NCT02016196	Rifaximin vs Placebo for the Prevention of Encephalopathy in Patients Treated by TIPS	https://ClinicalTrials.gov/show/NCT02016196	Completed	University Hospital, Toulouse	2017-07-31
NCT01966419	Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE)	https://ClinicalTrials.gov/show/NCT01966419	Completed	Mallinckrodt	2016-12-31
NCT01936246	Protein Supplementation in Infants With Brain Injury	https://ClinicalTrials.gov/show/NCT01936246	Completed	Children’s Hospital Medical Center, Cincinnati	2014-03-31
NCT01915368	Determining Optimal Post-Stroke Exercise (DOSE)	https://ClinicalTrials.gov/show/NCT01915368	Completed	University of British Columbia	2019-12-31
NCT01862250	Safety of Clonidine in Infants With Hypoxic Ischemic Encephalopathy During Therapeutic Hypothermia	https://ClinicalTrials.gov/show/NCT01862250	Completed	Johns Hopkins University	2015-04-14
NCT01847651	Brain Muscle Axis During Treatment of Hepatic Encephalopathy With L-ornithine L-aspartate	https://ClinicalTrials.gov/show/NCT01847651	Completed	Imperial College London	2015-06-30
NCT01846663	Efficacy, Safety, And Pharmacokinetics Of Rifaximin In Subjects With Severe Hepatic Impairment And Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT01846663	Recruiting	Bausch Health Americas, Inc.	2021-05-31
NCT01842581	The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT01842581	Completed	Bausch Health Americas, Inc.	2014-12-17
NCT01793129	Preemie Hypothermia for Neonatal Encephalopathy	https://ClinicalTrials.gov/show/NCT01793129	Recruiting	NICHD Neonatal Research Network	2020-08-31
NCT01773538	Diagnosis of Covert/Minimal Hepatic Encephalopathy by Means of Continuous Reaction Time Measurement	https://ClinicalTrials.gov/show/NCT01773538	Completed	Hospital of South West Jutland	2015-10-31
NCT01765218	Topiramate in Neonates Receiving Whole Body Cooling for Hypoxic Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT01765218	Recruiting	University of California, Davis	2020-05-31
NCT01760629	Hypothermia for Encephalopathy in Low Income Countries-Feasibilty	https://ClinicalTrials.gov/show/NCT01760629	Completed	Thayyil, Sudhin	2014-12-31
NCT01722578	L-ornithine L-aspartate in Overt Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT01722578	Completed	Dayanand Medical College and Hospital	2017-01-31
NCT01683383	California Transport Cooling Trial	https://ClinicalTrials.gov/show/NCT01683383	Completed	Stanford University	2013-10-31
NCT01662414	Effect of Undenatured Cysteine-Rich Whey Protein Isolate (HMS 90®) in Patients With Parkinson’s Disease	https://ClinicalTrials.gov/show/NCT01662414	Completed	Chulalongkorn University	2012-12-31
NCT01649648	Autologous Cord Blood Cells for Brain Injury in Term Newborns	https://ClinicalTrials.gov/show/NCT01649648	Completed	National University Hospital, Singapore	2013-11-30
NCT01624311	Pilot Study For Hypothermia Treatment In Hyperammonemic Encephalopathy In Neonates And Very Young Infants	https://ClinicalTrials.gov/show/NCT01624311	Completed	Columbia University	2015-05-31
NCT01613417	Comparison of Prohance® With Gadovist®/Gadavist™ in Magnetic Resonance Imaging (MRI) of the Brain	https://ClinicalTrials.gov/show/NCT01613417	Completed	Bracco Diagnostics, Inc	2014-04-30
NCT01559519	Post Transjugular Intrahepatic Portosystemic Shunt (Tips) Albumine Infusion to Prevent Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT01559519	Completed	University of Roma La Sapienza	2013-12-31
NCT01556646	Effect of Tolvaptan on Cognitive Function in Cirrhosis	https://ClinicalTrials.gov/show/NCT01556646	Completed	Hunter Holmes Mcguire Veteran Affairs Medical Center	2013-06-30
NCT01471015	Darbe Administration in Newborns Undergoing Cooling for Encephalopathy	https://ClinicalTrials.gov/show/NCT01471015	Completed	University of Utah	2014-01-31
NCT01343667	GORE Flow Reversal System and GORE Embolic Filter Extension Study	https://ClinicalTrials.gov/show/NCT01343667	Completed	W.L.Gore & Associates	2013-11-30
NCT04436601	Polyethylene Glycol Versus Lactulose on Hepatic Encephalopathy in Patients With Cirrhosis;(PEGHE Trial)	https://ClinicalTrials.gov/show/NCT04436601	Recruiting	Aga Khan University	2020-12-31
NCT04405544	Determination of Acute Encephalopathy Predictors in Patients With COVID-19	https://ClinicalTrials.gov/show/NCT04405544	Recruiting	State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia	2020-07-22
NCT04360148	Th Effect of Ketogenic Metabolic Nutritional Pattern on High-frequency Episodic Migraine (EMIKETO)	https://ClinicalTrials.gov/show/NCT04360148	Active, not recruiting	New Penta SRL	2020-09-14
NCT04325230	Prognostic Value of Arterial Spin Labeling Brain Perfusion MRI in Term Neonates With Hypoxic-ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT04325230	Recruiting	University Hospital, Bordeaux	2022-07-15
NCT04313686	Mindfulness-based Intervention to Promote Psychological Wellbeing in People With Epilepsy	https://ClinicalTrials.gov/show/NCT04313686	Active, not recruiting	University of Malaya	2019-12-10
NCT04286516	Brain Connections for Arm Movement After Stroke	https://ClinicalTrials.gov/show/NCT04286516	Recruiting	VA Pittsburgh Healthcare System	2020-11-30
NCT04283253	Predictors of Response in Chronic Stroke	https://ClinicalTrials.gov/show/NCT04283253	Recruiting	VA Pittsburgh Healthcare System	2020-08-28
NCT04261335	The Clinical Trial of CL2020 Cells for Neonatal Hypoxic Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT04261335	Recruiting	Nagoya University	2021-12-31
NCT04238416	Intravenous Branched Chain Amino Acids for Hepatic Encephalopathy in ACLF	https://ClinicalTrials.gov/show/NCT04238416	Recruiting	Postgraduate Institute of Medical Education and Research	2022-09-30
NCT04228653	Long-Term Follow-up Safety After DDS Implantation With/Without CDNF Infusions	https://ClinicalTrials.gov/show/NCT04228653	Enrolling by invitation	Renishaw	2022-09-20
NCT04220606	1H Magnetic Resonance Spectroscopy in Migraine Patients	https://ClinicalTrials.gov/show/NCT04220606	Completed	Leiden University Medical Center	2016-04-30
NCT04205838	Anakinra in Preventing Severe Chimeric Antigen Receptor T-Cell Related Encephalopathy Syndrome in Patients With Recurrent or Refractory Large B-cell Lymphoma	https://ClinicalTrials.gov/show/NCT04205838	Recruiting	Jonsson Comprehensive Cancer Center	2021-12-01
NCT04188834	Effects of Sensory Flicker and Electrical Flicker Stimulation.	https://ClinicalTrials.gov/show/NCT04188834	Recruiting	Emory University	2022-10-31
NCT04161053	Efficacy and Safety of Nitazoxanide in Preventing Recurrence of Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT04161053	Recruiting	Tanta University	2028-11-30
NCT04114981	Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease	https://ClinicalTrials.gov/show/NCT04114981	Recruiting	Alliance for Clinical Trials in Oncology	2025-03-31
NCT04096014	Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT04096014	Recruiting	The Cleveland Clinic	2020-06-30
NCT04076826	Adjunctive Sedation With Dexmedetomidine for the Prevention of Severe Inflammation and Septic Encephalopathy	https://ClinicalTrials.gov/show/NCT04076826	Recruiting	University Hospital Inselspital, Berne	2021-01-30
NCT04073290	Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and Lactulose	https://ClinicalTrials.gov/show/NCT04073290	Recruiting	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	2022-09-30
NCT04067622	Novel Arm Restraint For Critically Ill Patients To Reduce Immobility, Sedation, Agitation and Cognitive Impairment	https://ClinicalTrials.gov/show/NCT04067622	Recruiting	University of Vermont	2021-05-01
NCT04063215	A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy for the Treatment of Traumatic Brain Injury and Hypoxic-Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT04063215	Recruiting	Hope Biosciences	2021-08-29
NCT04054453	Prevention of Epilepsy by Reducing Neonatal Encephalopathy	https://ClinicalTrials.gov/show/NCT04054453	Recruiting	Thayyil, Sudhin	2023-08-01
NCT04014413	Safety and Efficacy of Fecal Microbiota Transplantation	https://ClinicalTrials.gov/show/NCT04014413	Recruiting	Chinese University of Hong Kong	2023-10-31
NCT03994822	pRESET for Occlusive Stroke Treatment	https://ClinicalTrials.gov/show/NCT03994822	Recruiting	phenox Inc.	2020-12-31
NCT03987893	PEG3350 in ACLF With Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT03987893	Recruiting	Postgraduate Institute of Medical Education and Research	2020-05-25
NCT03961087	Coenzyme Q10 and Meclofenoxate in Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT03961087	Recruiting	Zagazig University	2020-01-01
NCT03955432	Long-term Cardiac Monitoring in Epilepsy	https://ClinicalTrials.gov/show/NCT03955432	Recruiting	Northwell Health	2022-03-31
NCT03944447	Outcomes Mandate National Integration With Cannabis as Medicine	https://ClinicalTrials.gov/show/NCT03944447	Recruiting	OMNI Medical Services, LLC	2025-12-31
NCT03936777	A Study to Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome	https://ClinicalTrials.gov/show/NCT03936777	Enrolling by invitation	Zogenix, Inc.	2023-04-30
NCT03926351	High Dose Omega 3 in People at Risk for Dementia	https://ClinicalTrials.gov/show/NCT03926351	Recruiting	University Hospital, Akershus	2019-10-31
NCT03913221	Caffeine for Hypoxic-Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT03913221	Recruiting	University of North Carolina, Chapel Hill	2020-08-31
NCT03865771	Sleep Related Memory Consolidation in Children With Age Related Focal Epilepsy.	https://ClinicalTrials.gov/show/NCT03865771	Recruiting	University Hospital, Strasbourg, France	2020-09-30
NCT03837717	The Impact of Holding on Stress and Bonding in Mother-Infant Pairs During Therapeutic Hypothermia	https://ClinicalTrials.gov/show/NCT03837717	Recruiting	Maine Medical Center	2020-10-31
NCT03806816	Use of Melatonin for Neuroprotection in Asphyxiated Newborns	https://ClinicalTrials.gov/show/NCT03806816	Recruiting	University Hospital of Ferrara	2021-12-31
NCT03796598	FMT in Cirrhosis and Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT03796598	Recruiting	VA Office of Research and Development	2023-06-01
NCT03779672	Memantine for Epileptic Encephalopathy	https://ClinicalTrials.gov/show/NCT03779672	Recruiting	McGill University Health Centre/Research Institute of the McGill University Health Centre	2021-08-31
NCT03776994	Venezuelan Equine Encephalitis Monovalent Virus-Like Particle Vaccine	https://ClinicalTrials.gov/show/NCT03776994	Active, not recruiting	SRI International	2020-07-31
NCT03751085	A Clinical Study on Albert Wong Frame-based Stereotactic Biopsy System for Brain	https://ClinicalTrials.gov/show/NCT03751085	Recruiting	Ministry of Health, Malaysia	2020-07-17
NCT03717922	Low Intensity Focused Ultrasound for Learning and Memory	https://ClinicalTrials.gov/show/NCT03717922	Recruiting	University of California, Los Angeles	2023-10-31
NCT03706417	Telemedicine to Improve Use of Therapeutic Hypothermia in Rural Settings	https://ClinicalTrials.gov/show/NCT03706417	Recruiting	Maine Medical Center	2021-05-01
NCT03703622	Video-Debriefing for Improved Competence Among Skilled Birth Attendants in Lira District-Northern Uganda	https://ClinicalTrials.gov/show/NCT03703622	Recruiting	Makerere University	2018-12-31
NCT03635450	Study of hCT-MSC in Newborn Infants With Moderate or Severe HIE	https://ClinicalTrials.gov/show/NCT03635450	Active, not recruiting	Duke University	2019-07-28
NCT03585257	HEAL STUDY (Hepatic Encephalopathy and Albumin Study)	https://ClinicalTrials.gov/show/NCT03585257	Recruiting	Hunter Holmes Mcguire Veteran Affairs Medical Center	2020-06-20
NCT03535142	Prognostic Significance of Fatty Liver Disease in Bariatric Patients	https://ClinicalTrials.gov/show/NCT03535142	Recruiting	Hospital of South West Jutland	2035-06-01
NCT03525431	Clinical Utility of Pediatric Whole Exome Sequencing	https://ClinicalTrials.gov/show/NCT03525431	Recruiting	University of California, San Francisco	2021-04-30
NCT03515044	Rifaximin Soluble Solid Dispersion (SSD) Tablets Plus Lactulose for the Treatment of Overt Hepatic Encephalopathy (OHE)	https://ClinicalTrials.gov/show/NCT03515044	Recruiting	Bausch Health Americas, Inc.	2019-05-31
NCT03493204	Tackling 30-day Readmissions in Patients With Cirrhosis: The SALTYFOOD Trial	https://ClinicalTrials.gov/show/NCT03493204	Completed	University of Michigan	2019-08-19
NCT03466528	Alcohol: Thiamine and or Magnesium 1	https://ClinicalTrials.gov/show/NCT03466528	Completed	Glasgow Royal Infirmary	2018-04-02
NCT03460587	Long-term Telerehabilitation for Patients With Stroke	https://ClinicalTrials.gov/show/NCT03460587	Completed	University of California, Irvine	2019-03-31
NCT03448159	Fluoxetine Opens Window to Improve Motor Recovery After Stroke	https://ClinicalTrials.gov/show/NCT03448159	Recruiting	University Health Network, Toronto	2020-09-30
NCT03439982	Fecal Transplant for Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT03439982	Recruiting	University of Alberta	2023-04-12
NCT03432871	Nicotinamide Riboside and Mitochondrial Biogenesis	https://ClinicalTrials.gov/show/NCT03432871	Recruiting	Cambridge University Hospitals NHS Foundation Trust	2019-12-31
NCT03420482	Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT03420482	Recruiting	Massachusetts General Hospital	2021-12-31
NCT03414333	To Determine the Effect of GLP1 on Cognitive Function, Brain Glucose Metabolism and Neuroplasticity.	https://ClinicalTrials.gov/show/NCT03414333	Completed	University of Pisa	2017-06-30
NCT01241019	Safety and Efficacy of Topiramate in Neonates With Hypoxic Ischemic Encephalopathy Treated With Hypothermia	https://ClinicalTrials.gov/show/NCT01241019	Completed	Azienda Ospedaliero, Universitaria Meyer	2013-12-31
NCT01223768	Acetyl-L-Carnitine In Severe Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT01223768	Completed	University of Catania	NA
NCT01223742	Oral Acetyl-L-Carnitine Therapy Reduces Fatigue In Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT01223742	Completed	University of Catania	NA
NCT01223729	Acetyl-L-Carnitine Reduces Depression and Improves Quality of Life in Patients With Minimal Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT01223729	Completed	University of Catania	NA
NCT01218568	Rifaximin Plus Lactulose Versus Lactulose Alone for the Treatment of Hepatic Encephalopathy: a Double Blind Randomized Trial	https://ClinicalTrials.gov/show/NCT01218568	Completed	Institute of Liver and Biliary Sciences, India	2012-09-30
NCT01135628	Hyperproteic Diet Plus Lactobacillus Reuteri and Nitazoxanide in Minimal Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT01135628	Completed	Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran	2014-05-31
NCT01110447	Secondary Prophylaxis of Hepatic Encephalopathy With a Probiotic Preparation	https://ClinicalTrials.gov/show/NCT01110447	Completed	CD Pharma India Pvt. Ltd.	2013-03-31
NCT01083797	Sedation to Electroencephalography With Dexmedetomidine or Chloral Hydrate	https://ClinicalTrials.gov/show/NCT01083797	Completed	Federal University of Minas Gerais	2013-03-31
NCT01080144	Feasibility of Critical Flicker Frequency Procedure for the Diagnosis of Minimal Encephalopathy	https://ClinicalTrials.gov/show/NCT01080144	Completed	University Hospital, Toulouse	2012-10-31
NCT01069133	Study of Rifaximin in Minimal Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT01069133	Completed	Hunter Holmes Mcguire Veteran Affairs Medical Center	2012-05-31
NCT01059461	Study of Cerebrolysin for Treatment of Infants With History of Neonatal Hypoxic Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT01059461	Completed	Ain Shams University	2013-09-30
NCT01059396	Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal	https://ClinicalTrials.gov/show/NCT01059396	Completed	Fundació Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau	2015-07-15
NCT02022137	Fructans, Lactitol and Lactose in Minimal Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT02022137	Completed	Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran	2015-08-31
NCT01041755	Efficacy of L-Ornithine L-Aspartate in Acute Hepatic Encephalopathy.	https://ClinicalTrials.gov/show/NCT01041755	Completed	Centro Regional para el Estudio de las Enfermedades Digestivas	2011-12-31
NCT01027715	The Impact of Electroencephalographic (EEG) Seizure Treatment in Neonatal Encephalopathy	https://ClinicalTrials.gov/show/NCT01027715	Completed	Washington University School of Medicine	2015-12-31
NCT01008293	Effect of Probiotics in Treatment of Minimal Hepatic Encephalopathy (MHE) and Health Related Quality of Life	https://ClinicalTrials.gov/show/NCT01008293	Completed	CD Pharma India Pvt. Ltd.	2012-06-30
NCT00999167	A Study of Safety and Efficacy of HPN-100 in Subjects With Cirrhosis and Episodic Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT00999167	Completed	Horizon Pharma Ireland, Ltd., Dublin Ireland	2012-04-30
NCT00992290	Probiotic Lactobacillus GG (LGG) in Patients With Minimal Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT00992290	Completed	Virginia Commonwealth University	2012-12-31
NCT00986895	A Study of Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group	https://ClinicalTrials.gov/show/NCT00986895	Completed	Horizon Pharma Ireland, Ltd., Dublin Ireland	NA
NCT00955500	Effects of Proteins in Patients With Cirrhosis and Prior Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT00955500	Completed	Hospital Universitari Vall d’Hebron Research Institute	2008-01-31
NCT00945789	Erythropoietin in Infants With Hypoxic Ischemic Encephalopathy (HIE)	https://ClinicalTrials.gov/show/NCT00945789	Completed	Tanta University	2008-12-31
NCT00934700	Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal Asphyxia	https://ClinicalTrials.gov/show/NCT00934700	Completed	Imperial College London	2014-09-30
NCT00931060	Effects of Branched-Chain Amino Acids on Muscle Ammonia Metabolism in Patients With Cirrhosis and Healthy Subjects	https://ClinicalTrials.gov/show/NCT00931060	Completed	University of Aarhus	2009-06-30
NCT00914056	A Study of Controlled Lactulose Withdrawal	https://ClinicalTrials.gov/show/NCT00914056	Completed	Hunter Holmes Mcguire Veteran Affairs Medical Center	2009-05-31
NCT00890409	Safety and Efficacy of Hypothermia to Treat Neonatal Hypoxic-Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT00890409	Completed	Fudan University	2004-06-30
NCT00887562	Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like Episodes	https://ClinicalTrials.gov/show/NCT00887562	Completed	Columbia University	2012-07-31
NCT00886925	Efficacy of Albumin for Acute Encephalopathy in Patients With Cirrhosis	https://ClinicalTrials.gov/show/NCT00886925	Completed	Hospital Universitari Vall d’Hebron Research Institute	2012-07-31
NCT00862459	Dose Finding Study of Gadavist in Central Nervous System (CNS) Magnetic Resonance Imaging (MRI)	https://ClinicalTrials.gov/show/NCT00862459	Completed	Bayer	2007-03-31
NCT00839358	Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation	https://ClinicalTrials.gov/show/NCT00839358	Completed	Hospital Clinic of Barcelona	2016-02-29
NCT04082780	Rifamycin in Minimal Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT04082780	Recruiting	Hunter Holmes Mcguire Veteran Affairs Medical Center	2020-09-15
NCT03650452	A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Patients With Developmental and/or Epileptic Encephalopathies	https://ClinicalTrials.gov/show/NCT03650452	Active, not recruiting	Takeda	2020-09-30
NCT00867698	AST-120 Used to Treat Mild Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT00867698	Completed	Ocera Therapeutics	2010-04-30
NCT00831337	Evaluation of Probiotics in the Treatment of Portal Hypertension	https://ClinicalTrials.gov/show/NCT00831337	Completed	Pomeranian Medical University Szczecin	2010-11-30
NCT00829361	Stroke Telemedicine for Arizona Rural Residents Trial	https://ClinicalTrials.gov/show/NCT00829361	Completed	Mayo Clinic	2011-10-31
NCT04260035	The Effects of a Long-lasting Infusion of Vasoactive Intestinal Peptide (VIP) in Episodic Migraine Patients	https://ClinicalTrials.gov/show/NCT04260035	Recruiting	Danish Headache Center	2020-06-30
NCT03805009	Efficacy of End-Effector Robot-Assisted Gait Training in Subacute Stroke Patients	https://ClinicalTrials.gov/show/NCT03805009	Completed	IRCCS San Raffaele	2017-12-31
NCT02959294	Use of Adipose-Derived Stem/Stromal Cells in Concussion and Traumatic Brain Injuries	https://ClinicalTrials.gov/show/NCT02959294	Recruiting	Healeon Medical Inc	2023-11-30
NCT02017119	Comparison Between Lactulose and Lactulose-Paraffin in Cirrhotic Patients	https://ClinicalTrials.gov/show/NCT02017119	Completed	Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran	2014-05-31
NCT00808704	Neurological Outcome After Erythropoietin Treatment for Neonatal Encephalopathy	https://ClinicalTrials.gov/show/NCT00808704	Completed	Zhengzhou University	2008-07-31
NCT01446523	S. Endotoxin, Inflammatory Mediators and MRS Before and After Treatment in MHE	https://ClinicalTrials.gov/show/NCT01446523	Completed	Govind Ballabh Pant Hospital	2012-02-29
NCT03911388	HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors	https://ClinicalTrials.gov/show/NCT03911388	Recruiting	University of Alabama at Birmingham	2023-09-01
NCT03724136	Alzheimer’s Autism and Cognitive Impairment Stem Cell Treatment Study	https://ClinicalTrials.gov/show/NCT03724136	Recruiting	MD Stem Cells	2022-10-24
NCT03196739	Feasibility of Virtual Reality Games Using Head-mounted Display on Patients With Brain Disorders	https://ClinicalTrials.gov/show/NCT03196739	Completed	Seoul National University Hospital	2018-05-30
NCT02894866	Hyperbaric Oxygen Therapy Improves Outcome of Hypoxic-Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT02894866	Recruiting	Nanfang Hospital of Southern Medical University	2020-09-30
NCT02811263	High-dose Erythropoietin for Asphyxia and Encephalopathy	https://ClinicalTrials.gov/show/NCT02811263	Active, not recruiting	University of California, San Francisco	2022-01-31
NCT03775538	Safety of CDNF by Brain Infusion in Patients With Parkinson’s Disease. Extension to HP-CD-CL-2002 Clinical Study	https://ClinicalTrials.gov/show/NCT03775538	Active, not recruiting	Herantis Pharma Plc.	2020-06-30
NCT03712280	MNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy)	https://ClinicalTrials.gov/show/NCT03712280	Recruiting	Mallinckrodt	2020-08-31
NCT00772096	Septic Encephalopathy and Late Cognitive Dysfunction	https://ClinicalTrials.gov/show/NCT00772096	Completed	University Hospital, Basel, Switzerland	2011-06-30
NCT00764049	Single Pass Albumin Dialysis in Patients With Cirrhosis	https://ClinicalTrials.gov/show/NCT00764049	Completed	Assistance Publique - Hôpitaux de Paris	2012-01-31
NCT00719407	Neonatal Erythropoietin in Asphyxiated Term Newborns	https://ClinicalTrials.gov/show/NCT00719407	Completed	University of California, San Francisco	2011-09-30
NCT00686920	Safety and Tolerability Study of Rifaximin in Participants With a History of Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT00686920	Completed	Bausch Health Americas, Inc.	2010-12-08
NCT02079766	18F-AV-1451 and Florbetapir F 18 PET Imaging in Subjects at Risk for Chronic Traumatic Encephalopathy	https://ClinicalTrials.gov/show/NCT02079766	Completed	Avid Radiopharmaceuticals	2015-10-31
NCT00655304	The Effect of Prometheus (R) Liver Support Dialysis on Cerebral Metabolism in Acute Liver Failure	https://ClinicalTrials.gov/show/NCT00655304	Completed	Rigshospitalet, Denmark	2010-12-31
NCT00649207	A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases	https://ClinicalTrials.gov/show/NCT00649207	Completed	AbbVie	2013-03-31
NCT00624871	Ascorbic Acid and Ibuprofen in Infants With Hypoxic Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT00624871	Completed	Al-Azhar University	2006-04-30
NCT00620711	Pilot Study of Head Cooling in Preterm Infants With Hypoxic Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT00620711	Completed	Vanderbilt University Medical Center	2013-07-31
NCT00614744	Late Hypothermia for Hypoxic-Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT00614744	Completed	NICHD Neonatal Research Network	2016-06-30
NCT00593242	Cord Blood for Neonatal Hypoxic-ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT00593242	Completed	Duke University	2017-01-31
NCT00570973	Band Ligation Versus Transjugular Intrahepatic Portosystemic Stent Shunt (TIPS) in Cirrhotics With Recurrent Variceal Bleeding Non Responding to Medical Therapy	https://ClinicalTrials.gov/show/NCT00570973	Completed	Medical University of Vienna	2011-05-31
NCT00558038	Safety and Efficacy of AST-120 Compared to Lactulose in Patients With Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT00558038	Completed	Ocera Therapeutics	2009-03-31
NCT00537017	Follow Up Safety Study of SCH 420814 in Subjects With Parkinson’s Disease (P05175)	https://ClinicalTrials.gov/show/NCT00537017	Completed	Merck Sharp & Dohme Corp.	2009-11-19
NCT00533910	Rifaximin in Minimal Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT00533910	Completed	Hunter Holmes Mcguire Veteran Affairs Medical Center	2010-04-30
NCT00515359	RCT for Intermittent Versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies	https://ClinicalTrials.gov/show/NCT00515359	Completed	Spectrum Health Hospitals	2009-02-28
NCT00433368	Efficacy of L-Ornithine-L-Aspartate in Cirrhotics With Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT00433368	Completed	Aga Khan University	NA
NCT00406029	Dyskinesia in Parkinson’s Disease (Study P04501)	https://ClinicalTrials.gov/show/NCT00406029	Completed	Merck Sharp & Dohme Corp.	2008-10-05
NCT00383305	CoolCap Trial, Treatment of Perinatal Hypoxic-Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT00383305	Completed	Olympic Medical	NA
NCT00375375	Effect of Lactulose on Minimal Hepatic Encephalopathy and Health-Related Quality of Life	https://ClinicalTrials.gov/show/NCT00375375	Completed	Postgraduate Institute of Medical Education and Research	NA
NCT00312078	Effect of Yogurt on Minimal Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT00312078	Completed	Medical College of Wisconsin	NA
NCT00305591	Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment.	https://ClinicalTrials.gov/show/NCT00305591	Completed	Imperial College London	NA
NCT00298038	A 6-month Efficacy, Safety, and Tolerability Study of Rifaximin In Preventing Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT00298038	Completed	Bausch Health Americas, Inc.	2008-08-15
NCT00287235	Efficacy of Albumin Dialysis to Treat Patients With Hepatic Encephalopathy Using The Molecular Adsorbent Recirculating System (MARS)	https://ClinicalTrials.gov/show/NCT00287235	Completed	Baxter Healthcare Corporation	2003-11-30
NCT00248625	N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver Failure	https://ClinicalTrials.gov/show/NCT00248625	Completed	University of Pittsburgh	2009-09-30
NCT00240695	A Follow-up Study to Assess Safety and Tolerability of Galantamine Treatment in Individuals With Mild Cognitive Impairment	https://ClinicalTrials.gov/show/NCT00240695	Completed	Johnson & Johnson Pharmaceutical Research & Development, L.L.C.	NA
NCT00216502	A Study of the Safety and Effectiveness of Galantamine in Patients With Alzheimer’s Disease	https://ClinicalTrials.gov/show/NCT00216502	Completed	Janssen-Cilag S.p.A.	NA
NCT00147030	TOBY (TOtal Body hYpothermia): a Study of Treatment for Perinatal Asphyxia	https://ClinicalTrials.gov/show/NCT00147030	Completed	Imperial College London	2006-11-30
NCT00097097	Neonatal Resuscitation in Zambia	https://ClinicalTrials.gov/show/NCT00097097	Completed	NICHD Global Network for Women’s and Children’s Health	NA
NCT04445831	A Study to Evaluate the Safety, Tolerability and Immunogenicity of Tau Targeted Vaccines in Participants With Early Alzheimer’s Disease	https://ClinicalTrials.gov/show/NCT04445831	Recruiting	AC Immune SA	2022-10-31
NCT00000982	A Study of Azidothymidine in HIV-Infected Children	https://ClinicalTrials.gov/show/NCT00000982	Completed	National Institute of Allergy and Infectious Diseases (NIAID)	1996-09-30
NCT00614978	Lapatinib and Temozolomide for the Treatment of Progressive Brain Disease in HER-2 Positive Breast Cancer	https://ClinicalTrials.gov/show/NCT00614978	Completed	Jules Bordet Institute	2011-06-30
NCT00817401	Systemic Hypothermia Improves Outcome of Hypoxic-Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT00817401	Completed	Zhengzhou University	2008-06-30
NCT00004796	Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis	https://ClinicalTrials.gov/show/NCT00004796	Completed	Office of Rare Diseases (ORD)	NA

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT00645645	A Study of the Genetic Analysis of Brain Disorders	https://ClinicalTrials.gov/show/NCT00645645	Recruiting	National Institutes of Health Clinical Center (CC)	NA
NCT03338270	Clinical Validation Study of Multi-EPI Mix	https://ClinicalTrials.gov/show/NCT03338270	Completed	Karolinska University Hospital	2018-05-07
NCT03323411	End-of-life Intervention for African American Dementia Caregivers	https://ClinicalTrials.gov/show/NCT03323411	Completed	University of Illinois at Chicago	2016-09-10
NCT03284528	Does Placenta Pathology Predict Outcome of Neonates With Hypoxic Ischemic Encephalopathy?"	https://ClinicalTrials.gov/show/NCT03284528	Completed	University Children’s Hospital, Zurich	2017-01-01
NCT03246243	Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk	https://ClinicalTrials.gov/show/NCT03246243	Recruiting	Boston Children’s Hospital	2021-12-18
NCT03218332	Post-Concussion Syndrome in Professional Athletes: A Multidisciplinary Study	https://ClinicalTrials.gov/show/NCT03218332	Recruiting	University Health Network, Toronto	2020-12-30
NCT03179553	Heart Beat Variability in Neonatal Encephalopathy	https://ClinicalTrials.gov/show/NCT03179553	Recruiting	Thayyil, Sudhin	2021-07-31
NCT03173196	Prospective Analysis of Septic Associated Encephalopathy Using the Non-invasive Acoustocerebrography-ACG	https://ClinicalTrials.gov/show/NCT03173196	Completed	University of Rostock	2017-07-10
NCT03133208	Sepsis Associated Encephalopathy (SAE) Biomarkers	https://ClinicalTrials.gov/show/NCT03133208	Recruiting	University of Florida	2021-04-18
NCT03024021	Cerebral Oxymetry and Neurological Outcome in Therapeutic Hypothermia	https://ClinicalTrials.gov/show/NCT03024021	Completed	Tepecik Training and Research Hospital	2018-09-30
NCT02983786	Detection of Cerebral Ischemia With a Noninvasive Neurometabolic Optical Monitor	https://ClinicalTrials.gov/show/NCT02983786	Active, not recruiting	University of Pennsylvania	2020-09-30
NCT02965144	Long Term Survivors of High-grade Glioma and Their Caregivers	https://ClinicalTrials.gov/show/NCT02965144	Completed	Rigshospitalet, Denmark	2017-06-30
NCT02910921	Individualized Prediction of Migraine Attacks Using a Mobile Phone App and Fitbit	https://ClinicalTrials.gov/show/NCT02910921	Completed	Second Opinion Health	2018-07-31
NCT02831010	A Multi-Center Cohort Study of Risk Factors and Outcomes of Encephalopathy of Prematurity in China	https://ClinicalTrials.gov/show/NCT02831010	Active, not recruiting	Children’s Hospital of Fudan University	2019-12-31
NCT02800018	Correlation of Risk Factors and Severity of Hypoxic-ischaemic Encephalopathy	https://ClinicalTrials.gov/show/NCT02800018	Completed	University Children’s Hospital, Zurich	2017-12-31
NCT02798185	The DIAGNOSE-CTE Research Project	https://ClinicalTrials.gov/show/NCT02798185	Active, not recruiting	Boston University	2023-07-31
NCT02793999	Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia	https://ClinicalTrials.gov/show/NCT02793999	Recruiting	Boston Children’s Hospital	2020-05-31
NCT02767622	Reversibility of Minimal Hepatic Encephalopathy Following Liver Transplantation	https://ClinicalTrials.gov/show/NCT02767622	Completed	Ain Shams University	2015-04-30
NCT02683915	Reno-protective Effect of Brain Cooling in Newborn With Hypoxia	https://ClinicalTrials.gov/show/NCT02683915	Completed	Mansoura University Children Hospital	2016-09-30
NCT02676063	Long Term Prognostic of Neonatal Hypoxic Ischemic Encephalopathy With Hypothermia Treatment	https://ClinicalTrials.gov/show/NCT02676063	Active, not recruiting	University Hospital, Grenoble	2019-03-31
NCT02639806	General Anesthesia for Endovascular Thrombectomy; A Pilot Study.	https://ClinicalTrials.gov/show/NCT02639806	Enrolling by invitation	University of Saskatchewan	2020-12-31
NCT02613858	Minimal HePatic Encephalopathy Among CiRrhotics. A Cross SEctional, Clinico-EpidEmiological, Multi-Centre, Study in Patients of PakisTan	https://ClinicalTrials.gov/show/NCT02613858	Completed	Abbott	2017-03-31
NCT01858285	Genetics of Severe Early Onset Epilepsies	https://ClinicalTrials.gov/show/NCT01858285	Recruiting	Boston Children’s Hospital	2030-12-31
NCT00009243	Natural History of Stroke: Cause and Development	https://ClinicalTrials.gov/show/NCT00009243	Recruiting	National Institutes of Health Clinical Center (CC)	NA
NCT02544100	Neonatal Neurologic Intensive Care Network of China	https://ClinicalTrials.gov/show/NCT02544100	Recruiting	Children’s Hospital of Fudan University	2020-12-30
NCT02520817	Antioxidants and Zinc Improving Minimal Hepatic Encephalopathy In Truck Drivers; a Pilot Study	https://ClinicalTrials.gov/show/NCT02520817	Completed	Mansoura University	2013-10-31
NCT02455830	Cytokines Associated With Cord Blood Cell Therapy for Neonatal Encephalopathy	https://ClinicalTrials.gov/show/NCT02455830	Active, not recruiting	Neonatal Encephalopathy Consortium, Japan	2020-03-31
NCT02445417	Brain Activity During Birth for Prediction of Newborns at Risk for Brain Injury	https://ClinicalTrials.gov/show/NCT02445417	Completed	Sharp HealthCare	2017-08-31
NCT02442986	Neurological Outcome in Surgical and Non-surgical Septic Patients	https://ClinicalTrials.gov/show/NCT02442986	Completed	University of Rostock	2017-03-31
NCT02435810	Inflammatory and Infectious Diseases of the Nervous System	https://ClinicalTrials.gov/show/NCT02435810	Recruiting	National Institutes of Health Clinical Center (CC)	2025-11-29
NCT02377947	A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study]	https://ClinicalTrials.gov/show/NCT02377947	Completed	Abbott	2016-03-31
NCT02349672	Clinical Utility of Serum Biomarkers for the Management of Neonatal Hypoxic Ischemic Encephalopathy (Control Levels)	https://ClinicalTrials.gov/show/NCT02349672	Completed	University of Florida	2017-06-30
NCT02288715	Relationship of Cerebral Perfusion Pressure Variability to Sepsis-associated Encephalopathy	https://ClinicalTrials.gov/show/NCT02288715	Completed	West China Hospital	2015-03-31
NCT02266563	Amyloid and Tauopathy PET Imaging in Acute and Chronic Traumatic Brain Injury	https://ClinicalTrials.gov/show/NCT02266563	Completed	Icahn School of Medicine at Mount Sinai	2017-12-21
NCT02264808	Developmental Outcomes	https://ClinicalTrials.gov/show/NCT02264808	Completed	University of Florida	2018-12-03
NCT02260271	Florida Neonatal Neurologic Network	https://ClinicalTrials.gov/show/NCT02260271	Enrolling by invitation	University of Florida	2021-01-31
NCT02211820	PET Imaging in Chronic Traumatic Encephalopathy	https://ClinicalTrials.gov/show/NCT02211820	Completed	National Institutes of Health Clinical Center (CC)	2016-06-20
NCT02083367	Default Mode Network fMRI Maps as a Predictive Index of Hepatic Encephalopathy Outcome	https://ClinicalTrials.gov/show/NCT02083367	Completed	OSF Healthcare System	2014-10-31
NCT01309711	Magnetic Resonance Biomarkers in Neonatal Encephalopathy	https://ClinicalTrials.gov/show/NCT01309711	Completed	Thayyil, Sudhin	2017-08-13
NCT02055248	Study on Moebius Syndrome and Congenital Facial Weakness Disorders	https://ClinicalTrials.gov/show/NCT02055248	Completed	National Institutes of Health Clinical Center (CC)	2020-04-29
NCT02051894	NeoAdapt 3: Novel Biomarkers in the Evaluation of Neonatal Circulatory Insufficiency in Babies Suffering From Hypoxic Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT02051894	Completed	Brighton and Sussex University Hospitals NHS Trust	2016-09-30
NCT02019147	BiHiVE2 Study. The Investigation and Validation of Predictive Biomarkers in Hypoxic-ischaemic Encephalopathy.	https://ClinicalTrials.gov/show/NCT02019147	Completed	University College Cork	2017-08-31
NCT02003183	Traumatic Brain Injury and Risk for Chronic Traumatic Encephalopathy	https://ClinicalTrials.gov/show/NCT02003183	Completed	University of California, Los Angeles	2018-10-31
NCT01920347	The Neurological Pupil Index (NPi) on Intensive Care Unit (ICU) Trial	https://ClinicalTrials.gov/show/NCT01920347	Completed	Charite University, Berlin, Germany	2015-02-28
NCT01878305	Neuromonitoring of Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT01878305	Completed	University of Helsinki	2011-12-31
NCT01850914	Vascular Risk Factors in INPH-patients	https://ClinicalTrials.gov/show/NCT01850914	Completed	Umeå University	2012-07-31
NCT01754688	Determining Prevalence of Acute Bilirubin Encephalopathy in Developing Countries	https://ClinicalTrials.gov/show/NCT01754688	Completed	University of Minnesota	2015-02-28
NCT01747863	Prospective Research in Infants With Mild Encephalopathy	https://ClinicalTrials.gov/show/NCT01747863	Completed	McGill University Health Centre/Research Institute of the McGill University Health Centre	2015-12-31
NCT01694953	The Natural History Study of Mitochondrial NeuroGastroIntestinal Encephalopathy (MNGIE)	https://ClinicalTrials.gov/show/NCT01694953	Recruiting	Columbia University	2020-06-30
NCT01603953	Bioelectrical Impedance Vector Analysis in Cirrhotic Patients	https://ClinicalTrials.gov/show/NCT01603953	Completed	Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran	2013-12-31
NCT01597102	Cerebrovascular Autoregulation During and After Liver Transplantation	https://ClinicalTrials.gov/show/NCT01597102	Recruiting	Johannes Gutenberg University Mainz	2020-12-31
NCT01494064	Monitoring of Encephalopathy in Cirrhotic Patients Admitted in Intensive Care	https://ClinicalTrials.gov/show/NCT01494064	Completed	Assistance Publique - Hôpitaux de Paris	2014-10-31
NCT01481662	Epidemiological, Clinical and Etiological Features of SUSAC’s Syndrome	https://ClinicalTrials.gov/show/NCT01481662	Recruiting	Assistance Publique - Hôpitaux de Paris	2020-05-31
NCT01481207	Magnetic Resonance Imaging and Spectroscopy Biomarkers of Neonatal Hypoxic Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT01481207	Completed	University Children’s Hospital, Zurich	2019-07-09
NCT01425385	Autoregulation Assessment During Liver Transplantation	https://ClinicalTrials.gov/show/NCT01425385	Completed	Johns Hopkins University	2012-09-30
NCT04445649	Prognostic Factors to Regain Consciousness	https://ClinicalTrials.gov/show/NCT04445649	Recruiting	BDH-Klinik Hessisch Oldendorf	2023-06-15
NCT04424199	Temporal Disorders in Left and Right Brain-Damaged Patients	https://ClinicalTrials.gov/show/NCT04424199	Recruiting	Istituti Clinici Scientifici Maugeri SpA	2021-07-20
NCT04422925	s100β, NSE n GFAP in Living Donor Hepatectomy and Delirium	https://ClinicalTrials.gov/show/NCT04422925	Recruiting	Akdeniz University	2021-01-01
NCT04415294	Flicker App for Minimal Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT04415294	Recruiting	University of Washington	2021-10-22
NCT04359914	Neurocognitive Impairment in Patients With COVID-19	https://ClinicalTrials.gov/show/NCT04359914	Recruiting	University of Rostock	2020-12-31
NCT04290611	a Vigibase Pharmacovigilance Study of ENzalutamide Drug-induced neurotoxicitY	https://ClinicalTrials.gov/show/NCT04290611	Active, not recruiting	Groupe Hospitalier Pitie-Salpetriere	2025-01-01
NCT04156048	HIV&HEART Aging Study (12,5 Year Follow up)	https://ClinicalTrials.gov/show/NCT04156048	Completed	University Hospital, Essen	2019-10-31
NCT04131205	Role of MRI in Detection of Minimal Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT04131205	Recruiting	University Medical Centre Ljubljana	2023-06-01
NCT04077125	Transcranial Doppler Ultrasound and Minimal Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT04077125	Completed	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	2018-12-31
NCT04058327	A Study of MHE in Patients With Liver Diseases	https://ClinicalTrials.gov/show/NCT04058327	Recruiting	Tongji Hospital	2020-06-30
NCT04044248	TIPS Plus Transvenous Obliteration for Gastric Varices	https://ClinicalTrials.gov/show/NCT04044248	Recruiting	University of Illinois at Chicago	2021-04-04
NCT04042272	Evaluation of s100β, NSE and GFAP Levels in Renal Transplantation	https://ClinicalTrials.gov/show/NCT04042272	Recruiting	Akdeniz University	2020-07-15
NCT03968861	Outcome After 24 Months of Participants in the TOBY Xenon Study	https://ClinicalTrials.gov/show/NCT03968861	Completed	Guy’s and St Thomas’ NHS Foundation Trust	2017-06-30
NCT03938870	CNS Tau Kinetics in Healthy Aging and Alzheimer’s Disease	https://ClinicalTrials.gov/show/NCT03938870	Recruiting	Washington University School of Medicine	2021-03-31
NCT03934268	A Cohort Study on the Prognosis of Neonatal KCNQ2 Gene-associated Epileptic Encephalopathy	https://ClinicalTrials.gov/show/NCT03934268	Recruiting	Children’s Hospital of Fudan University	2022-12-31
NCT03847051	EPIMix Versus CT Brain Pediatric Study	https://ClinicalTrials.gov/show/NCT03847051	Recruiting	Karolinska University Hospital	2020-12-31
NCT03835039	The Ability of NIRS to Predict Brain Injury in Hypoxic Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT03835039	Recruiting	Albany Medical College	2024-12-31
NCT03744481	Becoming Children With Perinatal Anoxo-Ischemic Encephalopathy Without Indication of Therapeutic Hypothermia	https://ClinicalTrials.gov/show/NCT03744481	Completed	Hospices Civils de Lyon	2019-08-02
NCT03710278	The Effectiveness and Safety of Human Lumbar Puncture Assist Device (LPat)	https://ClinicalTrials.gov/show/NCT03710278	Completed	Spartanburg Regional Healthcare System	2019-01-23
NCT03663114	A Post-marketing Observational Study on Risk Factors for Hepatic Encephalopathy in Participants With Unresectable Hepatocellular Carcinoma	https://ClinicalTrials.gov/show/NCT03663114	Active, not recruiting	Eisai Inc.	2021-05-31
NCT03652246	Evaluation of the Diagnostic Contribution of High-throughput Exome Sequencing for Patients With Convulsive Encephalopathy of Unknown Etiology: Pilot Study to Improve Genetic Counselling	https://ClinicalTrials.gov/show/NCT03652246	Completed	Centre Hospitalier Universitaire Dijon	2014-09-30
NCT03640494	Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants	https://ClinicalTrials.gov/show/NCT03640494	Recruiting	Duke University	2020-08-31
NCT03592563	CUHK Brain Health Longitudinal Study	https://ClinicalTrials.gov/show/NCT03592563	Recruiting	Chinese University of Hong Kong	2038-12-31
NCT03586115	Minimal Hepatic Encephalopathy in Hereditary Hemorrhagic Telangiectasian	https://ClinicalTrials.gov/show/NCT03586115	Recruiting	University of Bari	2020-03-21
NCT03414021	Interest of the SPECT-CT Scan SUVspect in the New Generation of Gamma-cameras With Semiconductor	https://ClinicalTrials.gov/show/NCT03414021	Recruiting	Lille Catholic University	2023-01-30
NCT01238250	Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight	https://ClinicalTrials.gov/show/NCT01238250	Recruiting	Simons Searchlight	2050-10-31
NCT01151475	Cerebral Oxygen, Blood Flow and Ammonia Uptake in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy (HE)	https://ClinicalTrials.gov/show/NCT01151475	Completed	University of Aarhus	2011-08-31
NCT01099293	Cerebrovascular Reactivity in Hepatic Encephalopathy	https://ClinicalTrials.gov/show/NCT01099293	Completed	Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran	2011-06-30
NCT00986648	A Multi-Center Group to Study Acute Liver Failure in Children	https://ClinicalTrials.gov/show/NCT00986648	Completed	University of Pittsburgh	2015-12-31
NCT03129620	Pharmacokinetics of Ampicillin in Neonates With Moderate to Severe Hypoxic-Ischemic Encephalopathy	https://ClinicalTrials.gov/show/NCT03129620	Completed	Drexel University	2016-03-31
NCT04330287	HIV-HEART Aging Study (15 Year Follow up)	https://ClinicalTrials.gov/show/NCT04330287	Recruiting	University Hospital, Essen	2022-10-31
NCT02291081	A Prospective Observational Trial to Determine Cardiovascular Diseases in HIV-infected Patients	https://ClinicalTrials.gov/show/NCT02291081	Completed	University Hospital, Essen	2016-11-30
NCT03485781	Propofol-induced EEG Changes in Hypoxic Brain Injury	https://ClinicalTrials.gov/show/NCT03485781	Completed	University of Oulu	2019-07-10
NCT00697411	Study of Selected X-Linked Disorders: Aicardi Syndrome	https://ClinicalTrials.gov/show/NCT00697411	Recruiting	Baylor College of Medicine	2025-01-31
NCT00593203	Brain Tissue Specimen Collection	https://ClinicalTrials.gov/show/NCT00593203	Enrolling by invitation	Vanderbilt University Medical Center	2028-12-31
NCT00592709	Analysis of Brain Tumors Using Matrix Assisted Laser Desorption/Ionization Mass Spectrometry	https://ClinicalTrials.gov/show/NCT00592709	Completed	Vanderbilt University Medical Center	2010-12-31
NCT00581581	CoolCap Followup Study-Coordination of Participating Centers	https://ClinicalTrials.gov/show/NCT00581581	Completed	University of Rochester	2009-10-31
NCT00472732	Neurologic Injuries in Adults With Urea Cycle Disorders	https://ClinicalTrials.gov/show/NCT00472732	Completed	Children’s National Research Institute	2009-07-31
NCT00424957	Brain Energy Metabolism in Patients With Chronic Liver Disease and Impaired Central Nervous System	https://ClinicalTrials.gov/show/NCT00424957	Completed	University of Aarhus	2007-04-30
NCT00410111	Pathogenesis and Cerebrovascular Manifestations of Septic Encephalopathy	https://ClinicalTrials.gov/show/NCT00410111	Completed	University Hospital, Basel, Switzerland	NA
NCT00305305	Brain Development Research Program	https://ClinicalTrials.gov/show/NCT00305305	Recruiting	University of California, San Francisco	2025-01-31
NCT00291421	A Survey Study of the Treatment and Outcome Management in Patients Diagnosed With Alzheimer’s Disease	https://ClinicalTrials.gov/show/NCT00291421	Completed	Janssen Pharmaceutica N.V., Belgium	NA
NCT00237315	Longitudinal Study of Urea Cycle Disorders	https://ClinicalTrials.gov/show/NCT00237315	Recruiting	Children’s National Research Institute	2024-07-31
NCT00088426	Clinical and Genetic Studies on Holoprosencephaly	https://ClinicalTrials.gov/show/NCT00088426	Completed	National Institutes of Health Clinical Center (CC)	2020-03-16
NCT00024908	Test of A Model of Representational Knowledge Stored in the Human Prefrontal Cortex	https://ClinicalTrials.gov/show/NCT00024908	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001284	Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy Volunteers	https://ClinicalTrials.gov/show/NCT00001284	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00016510	Differences in Brain Processing of First and Second Languages (Korean and English)	https://ClinicalTrials.gov/show/NCT00016510	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001927	Study of Abnormal Blood Clotting in Children With Stroke	https://ClinicalTrials.gov/show/NCT00001927	Completed	National Institutes of Health Clinical Center (CC)	NA

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT04337697	Neonatal Seizure Registry - Developmental Functional EValuation	https://ClinicalTrials.gov/show/NCT04337697	Recruiting	University of California, San Francisco	2024-02-29
NCT03267615	VICIS - Vienna Cirrhosis Study	https://ClinicalTrials.gov/show/NCT03267615	Recruiting	Medical University of Vienna	2026-12-31
NCT03137355	The Leigh Syndrome Registry	https://ClinicalTrials.gov/show/NCT03137355	Recruiting	The University of Texas Health Science Center, Houston	2025-06-17
NCT02488993	Real World Outcomes Study of Hepatic Encephalopathy Patients’ Experience on Rifaximin (PROSPER)	https://ClinicalTrials.gov/show/NCT02488993	Completed	Norgine	2018-09-29
NCT02231060	Study for the Improvement of Long-Term Outcome Prediction in Patients in Coma After Cardiac Arrest	https://ClinicalTrials.gov/show/NCT02231060	Completed	Ludwig-Maximilians - University of Munich	2018-12-06
NCT04320472	Acute Encephalopathy in Critically Ill Patients With COVID-19	https://ClinicalTrials.gov/show/NCT04320472	Recruiting	Ictal Group	2020-12-31
NCT04001595	The Global FKRP Patient Registry	https://ClinicalTrials.gov/show/NCT04001595	Recruiting	Newcastle University	2020-12-31
NCT03897101	Inflammation and Metabolic Acidosis at Birth (AGAIN: AutophaGy AcIdosis Newborn)	https://ClinicalTrials.gov/show/NCT03897101	Recruiting	University Hospital of Ferrara	2019-12-31
NCT03858400	Electrophysiological Tests on Unconscious Patient	https://ClinicalTrials.gov/show/NCT03858400	Completed	Nevsehir Public Hospital	2018-03-31
NCT03470467	Posterior Reversible Encephalopathy Syndrome in the Critically Ill Patients	https://ClinicalTrials.gov/show/NCT03470467	Recruiting	Ictal Group	2028-12-31